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Chapter 205 of 2363 min read

Regulation and disorders

Why this is asked: Breathing rate is regulated mainly by CO2 and H+ levels sensed by the medulla's chemosensitive area, not by how much O2 is available — the opposite of the intuitive "we breathe because we need oxygen." Among disorders, emphysema is alveolar-wall damage that shrinks the gas-exchange surface (usually from chronic smoking), while asthma is inflammation of the bronchi and bronchioles causing wheezing, not alveolar damage.

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